Monday, 24 February 2014
Older fathers more likely to have 'mutant sperm'
They say that older fathers have a higher risk of fathering a child with a disorder such as autism or schizophrenia.
An increasing body of evidence is showing that as a man ages, his sperm becomes poorer quality.
This is because mutations cause stem cells in the testicles to divide abnormally, resulting in an increasing proportion of mutant sperm as men age, New Scientist reports.
Some studies have even linked having an older father to Alzheimer's disease, bipolar disorder (previously known as manic depression), heart disease and cancer.
Now, scientists warn that a man in his 40s is twice as likely to pass down potentially disease-forming genetic mutations as a man in his 20s - indicating that the biological clock ticks for men, too.
Plenty of high-profile men have become late-life fathers, including Steve Martin at 67, David at 53 and Des O'Connor, who became a father for the fifth time at 72.
For decades, scientists have speculated about links between older fathers and birth defects. But it was only recently that a groundbreaking study, published in the respected journal Nature, proved that men undoubtedly pass on more genetic mutations to their children as they get older.
Read more ...
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