Tuesday 19 April 2011

Woman with Turner Syndrome has a baby girl after receiving an ovary transplant from her twin sister

A Frenchwoman suffering from a chromosome disorder has given birth to a healthy daughter thanks to a ovarian transplant from her twin sister.

Doctors said the baby girl, called Victoria, is free of the disorder known as Turner Syndrome which affects both her mother and her aunt. Karine Thiriot, 39, gave birth to her 6lb 3oz daughter on March 8 this year at a private hospital in Le Chesnay, Paris.

'The mother and baby are doing well,' said Dr Guy Kerbrat, who delivered Victoria. The new mother had been trying to conceive, using in vitro fertilisation, for at least 15 years. Thiriot had no ovaries because of Turner Syndrome, which affects one girl in 2,500.

It occurs when one of the two X chromosomes that are found in females is completely or partially missing. It is not an inherited condition and occurs as a random event during the formation of reproductive cells.

Her twin sister Stephanie had a 'mosaic' form of the disorder, which meant it only affected some of her body's cells. She was fertile and managed to have two children.

In August 2009 Stephanie donated an ovary to Karine. Transplants between identical twins do not require anti-rejection treatment which would complicate a future pregnancy.

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